1 00:00:00,000 --> 00:00:05,000 I know about prize, it just been awarded for the discovery of Nitrocoxide and I was introduced to this new side. 2 00:00:05,000 --> 00:00:10,300 We knew a lot, but there was still so much that we didn't know, like how does the human body make it? 3 00:00:10,300 --> 00:00:15,300 Once it's produced, where does it go? What does it become? Perhaps most importantly, how do we restore the natural production of Nitrocoxide? 4 00:00:15,300 --> 00:00:20,300 What are professionals doing wrong? Where are we missing the mark? 5 00:00:20,300 --> 00:00:25,900 First, you have to read the book, it tells the story of Nitrocoxide, a secret of Nitrocoxide, and bring the science to life. 6 00:00:25,900 --> 00:00:29,700 If you're a high-performing athlete, number one, you have to get rid of fluoride in your toothpaste. 7 00:00:29,700 --> 00:00:33,400 Number two, our antiseptic mouthwash. And then third is get off an essence. 8 00:00:33,400 --> 00:00:37,400 We got to avoid sugar. Sugar's a toxin, sugar's the enemy, sugar's the poison. 9 00:00:37,400 --> 00:00:42,700 How do you personally define thriving and life in leadership? 10 00:00:42,700 --> 00:00:49,200 I think I would answer that question by having the liberty to do what I want to do, when I want to do it, and with whom I want to do that. 11 00:00:51,500 --> 00:01:00,800 Most of us are taught that aging is inevitable, that fatigue, brain fog, and decline just come with a territory. 12 00:01:00,800 --> 00:01:07,100 But what if your real biological age isn't tied to your birthday, but your biochemistry? 13 00:01:07,100 --> 00:01:15,100 Today, we're joined by Dr. Nathan Bryan, a global leader in molecular medicine and nitrocoxide research. 14 00:01:15,100 --> 00:01:27,100 We're talking about how you can extend your impact, upgrade your performance, and possibly add a decade or more to your health span all by getting your chemistry in check. 15 00:01:27,100 --> 00:01:29,900 Welcome Dr. Nathan. 16 00:01:29,900 --> 00:01:32,500 Wow, thanks. Great to be with you. 17 00:01:32,500 --> 00:01:34,800 Now let's start with your journey. 18 00:01:34,800 --> 00:01:41,000 What led you to dedicating your life to nitrocoxide research? 19 00:01:41,000 --> 00:01:44,900 And why is this such a game-changer for human health? 20 00:01:44,900 --> 00:01:47,000 Well, I think God has a sense of humor. 21 00:01:47,000 --> 00:01:55,800 I got a degree from biochemistry from the University of Texas at Austin, and once I got a degree, I swore I'd never want to deal with nitrogen-based chemistry again. 22 00:01:55,800 --> 00:02:03,800 Fast forward 30 years, and here we are, was still deep in the research of nitrogen-based chemistry, specifically nitrocoxide. 23 00:02:03,800 --> 00:02:06,500 Now, I was a student at LSU School of Medicine. 24 00:02:06,500 --> 00:02:10,600 I was working on a PhD in molecular and cellular physiology, and I know about prize. 25 00:02:10,600 --> 00:02:15,000 It's just been awarded for the discovery of nitrocoxide, and I was introduced to this new science. 26 00:02:15,000 --> 00:02:16,700 I mean, we knew it was important. 27 00:02:16,700 --> 00:02:23,700 You know, had a chance to interact and meet the guys who want to know about prize for the discovery of microcoxide as a sigma molecule. 28 00:02:23,700 --> 00:02:30,600 And just, you know, back then, we knew it was an important molecule, and so there was, we knew a lot, but there was still so much that we didn't know. 29 00:02:30,600 --> 00:02:32,200 How does the human body make it? 30 00:02:32,200 --> 00:02:33,700 Once it's produced, where does it go? 31 00:02:33,700 --> 00:02:35,700 What does it become? How does it signal? 32 00:02:35,700 --> 00:02:39,700 Perhaps most importantly, how do we restore the natural production of microcoxide? 33 00:02:39,700 --> 00:02:44,100 And, you know, one of the Nobel Prize winners told me, isn't it, if you can figure that out, you'll change the world. 34 00:02:44,100 --> 00:02:47,600 You know, change the landscape of medicine, health care. 35 00:02:47,600 --> 00:02:51,000 I love it, and God does have a sense of humor. 36 00:02:51,000 --> 00:02:52,000 That is for certain. 37 00:02:52,000 --> 00:02:55,600 If you would have told me 10 years ago, I'd be living in Texas. 38 00:02:55,600 --> 00:02:57,000 I would have laughed at you. 39 00:02:57,000 --> 00:03:01,300 But here I am, an official longhorn, and loving every minute of it. 40 00:03:01,300 --> 00:03:09,600 So, let's talk nitrocoxide and the rapidly aging executive that is, 41 00:03:09,600 --> 00:03:12,500 burnt out stress out, all the things. 42 00:03:12,500 --> 00:03:21,500 Tell me a little bit about how nitric oxide levels relate to aging, and what does that mean for high performers 43 00:03:21,500 --> 00:03:26,000 under ongoing, never stopping, constant stress. 44 00:03:26,000 --> 00:03:29,800 Ready to lead smarter and invest wiser? 45 00:03:29,800 --> 00:03:36,500 On the Executive Connect podcast, we unpack executive strategies for wealth and influence. 46 00:03:36,500 --> 00:03:40,900 Hit the subscribe button now. Don't just watch acts. 47 00:03:40,900 --> 00:03:48,500 Well, look, nitric oxide controls and regulates everything we know about longevity, health, human optimization. 48 00:03:48,500 --> 00:03:53,400 And so, when you look at what this molecule is and does, I mean, it's a gas that's produced by the lighting of the blood vessels, 49 00:03:53,400 --> 00:03:57,400 it's produced by our immune cells to keep, you know, to kill off invading pathogens. 50 00:03:57,400 --> 00:04:00,200 And it's a neurotransmit in the central nervous system. 51 00:04:00,200 --> 00:04:03,900 So, if you lose the ability to produce microcoxide, 52 00:04:03,900 --> 00:04:09,500 you have poor mitochondrial functions, your energy production capacity of the cell decreases. 53 00:04:09,500 --> 00:04:15,500 We have less stem cells in circulation, so we don't heal, we don't repair and replace dysfunctional cells. 54 00:04:15,500 --> 00:04:20,700 And then our telomeres get shorter, and we know that shorter telomeres equal shorter lifespan. 55 00:04:20,700 --> 00:04:27,200 So, we have to be able to maintain adequate nitric oxide production to live longer, healthier lives, 56 00:04:27,200 --> 00:04:31,300 and optimize our performance in any age. 57 00:04:31,300 --> 00:04:36,100 Yeah, and I have to believe that there is a major link between stress, inflammation, 58 00:04:36,100 --> 00:04:42,600 and how we're depleting our energy and immunity, and probably mental clarity these days 59 00:04:42,600 --> 00:04:46,400 when we're constantly on and never stopping. 60 00:04:46,400 --> 00:04:47,600 No, that's right. 61 00:04:47,600 --> 00:04:55,000 There's a clear connection between stress, nitric oxide deficiency, and the hallmarks of chronic disease. 62 00:04:55,000 --> 00:04:57,900 So, when we're stressed, we're always in this fight or flight mode, 63 00:04:57,900 --> 00:05:01,700 and we don't rest and digest and balance our autonomic nervous system. 64 00:05:01,700 --> 00:05:03,900 We get an up-regulation of cortisol. 65 00:05:03,900 --> 00:05:11,500 We balance out that cortisol curve and it leads to inflammation, oxidative stress, and immune dysfunction. 66 00:05:11,500 --> 00:05:14,500 And we know that when you become nitric oxide deficient, 67 00:05:14,500 --> 00:05:20,100 if you look at, for instance, dementia, malcognitive impairment, even erectile dysfunction, 68 00:05:20,100 --> 00:05:26,100 when we talk about performance, cognitive performance, sexual performance, or even athletic performance, 69 00:05:26,100 --> 00:05:28,300 we have to have adequate blood supply. 70 00:05:28,300 --> 00:05:32,300 We've got to be able to dilate the blood vessels of the brain, of the sex organs, or skeletal muscle, 71 00:05:32,300 --> 00:05:34,300 or hard, if you're going to exercise. 72 00:05:34,300 --> 00:05:38,700 We have to be able to deliver oxygen to individual cells. 73 00:05:38,700 --> 00:05:41,900 We have to optimize mitochondria, so the mitochondria can take that oxygen 74 00:05:41,900 --> 00:05:44,900 and make cellular energy or ATP. 75 00:05:44,900 --> 00:05:49,100 And so, then we've got to suppress the inflammation, oxidative stress, and immune dysfunction. 76 00:05:49,100 --> 00:05:51,000 And nitric oxide does all that. 77 00:05:51,000 --> 00:05:55,900 Dylates the blood vessels, improves tissue oxygenation, and produces mitochondrial biogenesis. 78 00:05:55,900 --> 00:06:00,100 Improves the efficiency of oxygen utilization in the mitochondria. 79 00:06:00,100 --> 00:06:07,100 And it mobilizes stem cells, so we've got more stem cells in circulation, and it inhibits oxidative stress. 80 00:06:07,100 --> 00:06:11,100 And then it corrects the immune dysfunction that we see in chronically ill patients. 81 00:06:11,100 --> 00:06:18,700 So it really is the holy grail in medicine, in longevity, and human optimization. 82 00:06:18,700 --> 00:06:20,300 Now, I'm curious. 83 00:06:20,300 --> 00:06:27,700 What is the biggest myth about longevity that you wish people in leadership, heavy leadership roles 84 00:06:27,700 --> 00:06:30,700 or the C-suite really understood? 85 00:06:30,700 --> 00:06:35,700 Are you someone with a demanding job, but tired of the 9-5 grind? 86 00:06:35,700 --> 00:06:41,700 What if you could build a profitable side hustle without sacrificing your full-time career? 87 00:06:41,700 --> 00:06:49,100 Our new partner, Book Profits, can show you how to turn your limited free time into a thriving online business. 88 00:06:49,100 --> 00:06:55,900 Learn how to find, sell, and profit from use books all on your schedule from the comfort of your own home. 89 00:06:55,900 --> 00:07:03,700 Not crazy tech skills needed and no major upfront investment, just simple strategies that fit into your busy lifestyle. 90 00:07:03,700 --> 00:07:11,300 Visit the URL on the screen for a free training today and learn more. 91 00:07:11,300 --> 00:07:20,500 The biggest myth is that if you're a for-profit company, if you're driven strictly by profits, you've missed the mark. 92 00:07:20,500 --> 00:07:26,700 And I think successful companies shouldn't focus strictly on profit. 93 00:07:26,700 --> 00:07:34,500 That's why I turned from a research scientist, a professor of molecular medicine into a founder and a CEO and executive, 94 00:07:34,500 --> 00:07:42,500 because I'd been in really bad organizations where the leadership was strictly defined and motivated by profits. 95 00:07:42,500 --> 00:07:44,500 And how do we make more money? 96 00:07:44,500 --> 00:07:48,700 And I think you lose your purpose. 97 00:07:48,700 --> 00:07:53,300 And I think what I've learned from that is, let science lead the way. 98 00:07:53,300 --> 00:07:58,300 When you're an executive in a company, number one, you have to develop a strategy and a mission. 99 00:07:58,300 --> 00:08:02,100 And you have to bring people together that drink the Kool-Aid. 100 00:08:02,100 --> 00:08:08,300 They believe what you're doing, they've bought in, and then you've got to put the right people in there to execute your strategy. 101 00:08:08,300 --> 00:08:12,300 And for us, nitric oxide is the guiding principle. 102 00:08:12,300 --> 00:08:17,300 And we develop products that, and we want to if you can make nitric oxide, we do it for you. 103 00:08:17,300 --> 00:08:19,100 And so our products work. 104 00:08:19,100 --> 00:08:22,300 And so we're not driven by profits. 105 00:08:22,300 --> 00:08:26,700 We're driven by constant innovation, delivering products that work. 106 00:08:26,700 --> 00:08:31,300 And number one, our main motivation was to maintain the integrity of the field. 107 00:08:31,300 --> 00:08:36,100 Because there's these companies out there who are selling so-called nitric oxide products. 108 00:08:36,100 --> 00:08:40,900 And I give emails and phone calls and texts every day from people who buy those products and go, 109 00:08:40,900 --> 00:08:44,500 Nathan, we hear you talking about nitric oxide all the time for the past decade. 110 00:08:44,500 --> 00:08:49,100 But you know what, I've been taking a nitric oxide product and it hasn't helped me. 111 00:08:49,100 --> 00:08:51,900 So nitric oxide doesn't work for me. 112 00:08:51,900 --> 00:08:56,500 And I go, "Whoa, whoa, whoa, that's a very dangerous interpretation." 113 00:08:56,500 --> 00:08:58,100 Nitric oxide always works. 114 00:08:58,100 --> 00:09:02,500 Now what done work for you is that company. 115 00:09:02,500 --> 00:09:04,500 What done work for you is that product. 116 00:09:04,500 --> 00:09:09,300 If you take a product and we generate nitric oxide, or we naturally improve your ability to produce nitric oxide, 117 00:09:09,300 --> 00:09:10,500 you will see the effect. 118 00:09:10,500 --> 00:09:12,300 You will perform better at cognitive. 119 00:09:12,300 --> 00:09:13,300 Your brain will be on. 120 00:09:13,300 --> 00:09:16,900 You'll perform better sexually when the blood vessels improve sexual function. 121 00:09:16,900 --> 00:09:21,900 If you're a high performing athlete, you're going to be more well trained. 122 00:09:21,900 --> 00:09:25,900 Because nitric oxide optimizes the efficiency of oxen utilization. 123 00:09:25,900 --> 00:09:29,700 So you can go longer, stronger, faster. 124 00:09:29,700 --> 00:09:31,300 So everything we know about that. 125 00:09:31,300 --> 00:09:35,500 So what my philosophy is, and our philosophy at Brighton Therapeutics is, 126 00:09:35,500 --> 00:09:36,700 look, just do the right thing. 127 00:09:36,700 --> 00:09:38,500 If you do the right thing, the cash register rings. 128 00:09:38,500 --> 00:09:42,500 But people get stressed out about profits, especially publicly traded companies 129 00:09:42,500 --> 00:09:47,500 who are always constantly figuring out how to maintain shareholder buy-in 130 00:09:47,500 --> 00:09:49,100 and maintain good share prices. 131 00:09:49,100 --> 00:09:53,500 And that's why I've avoided private equity, I've avoided venture capitalists. 132 00:09:53,500 --> 00:10:00,100 And I don't suffer from those same type of stresses or pressures. 133 00:10:00,100 --> 00:10:01,500 Yeah, I love what you're saying. 134 00:10:01,500 --> 00:10:04,100 I was thinking about, I'm an athlete. 135 00:10:04,100 --> 00:10:07,900 I always looked for my competitive edge that I could find 136 00:10:07,900 --> 00:10:11,700 with when I was running competitive leaders playing sports. 137 00:10:11,700 --> 00:10:16,500 But let's talk about stamina, recovery. 138 00:10:16,500 --> 00:10:19,300 What is the how behind it? 139 00:10:19,300 --> 00:10:24,500 Like how does nitric oxide give leaders an edge in decision-making 140 00:10:24,500 --> 00:10:27,500 and their focus and their performance? 141 00:10:27,500 --> 00:10:29,500 What's the how behind that? 142 00:10:29,500 --> 00:10:30,900 The how is really perfusion. 143 00:10:30,900 --> 00:10:34,700 So for any organ to work properly, including the brain, 144 00:10:34,700 --> 00:10:37,500 we have to adequately perfuse certain retres of the brain. 145 00:10:37,500 --> 00:10:37,700 Right? 146 00:10:37,700 --> 00:10:42,100 So our executive function, our memory recall, our cognitive function, 147 00:10:42,100 --> 00:10:46,300 when we're on, we've got to dilate blood vessels and recruit capillaries 148 00:10:46,300 --> 00:10:50,100 and perfuse certain retres of the brain to allow us to be on. 149 00:10:50,100 --> 00:10:54,100 And that's dictated and controlled by the production of nitric oxide. 150 00:10:54,100 --> 00:10:58,500 And you can see this in any patient with a neurological disease, 151 00:10:58,500 --> 00:11:03,500 whether it's ADHD, obsessive-compulsive disorder, addictive disorders, 152 00:11:03,500 --> 00:11:07,700 dementia, mild cognitive impairment, and Alzheimer's, 153 00:11:07,700 --> 00:11:11,100 that the common denominator in all those is there's a lack of regulation 154 00:11:11,100 --> 00:11:11,900 of blood flow. 155 00:11:11,900 --> 00:11:14,500 We call it focal ischemia or hypoxia in the brain. 156 00:11:14,500 --> 00:11:16,700 We're not dilating the blood vessels. 157 00:11:16,700 --> 00:11:20,900 We're not fully oxygenating that part of the brain and it doesn't function. 158 00:11:20,900 --> 00:11:23,100 So then we lose our cognitive ability. 159 00:11:23,100 --> 00:11:25,800 And in the earliest stages of that through, you know, 160 00:11:25,800 --> 00:11:29,100 spec schemes or functional MRI is looking at cerebral blood flow, 161 00:11:29,100 --> 00:11:30,700 that's really the first indication. 162 00:11:30,700 --> 00:11:33,700 That's why we call it vascular dementia at later stages, 163 00:11:33,700 --> 00:11:37,700 because it's a vascular disease and it's a metabolic disease. 164 00:11:37,700 --> 00:11:41,300 And nitric oxide controls the vascular and the metabolic aspects 165 00:11:41,300 --> 00:11:44,500 of cognitive performance. 166 00:11:44,500 --> 00:11:47,700 And really that's how we, you know, those are the high performers. 167 00:11:47,700 --> 00:11:51,100 The ones that can adequately produce nitric oxide and can 168 00:11:51,100 --> 00:11:53,900 refuse the brain and get glucose into the cell and there might 169 00:11:53,900 --> 00:11:56,900 a comrade work to produce cellular energy. 170 00:11:56,900 --> 00:12:00,100 Those are your high performance and it's not just the executives. 171 00:12:00,100 --> 00:12:07,300 It's the athletes and anyone that's considered high performing in any industry. 172 00:12:07,300 --> 00:12:09,500 I'm curious with, you know, 173 00:12:09,500 --> 00:12:15,300 I've seen a lot of younger people having heart attacks or strokes 174 00:12:15,300 --> 00:12:20,300 and I'm curious for say a 45 year old CEO, 175 00:12:20,300 --> 00:12:24,600 what's the difference between health span and lifespan 176 00:12:24,600 --> 00:12:27,900 and why should CEOs care about that right now? 177 00:12:27,900 --> 00:12:30,900 Well, look for me personally, you know, 178 00:12:30,900 --> 00:12:33,900 we have such a short time on earth, right? 179 00:12:33,900 --> 00:12:37,300 So every day I want to wake up and be better than I was yesterday 180 00:12:37,800 --> 00:12:41,700 and just really do the best I can to leave a lasting impact. 181 00:12:41,700 --> 00:12:43,600 But if I stress about things and I'm not healthy, 182 00:12:43,600 --> 00:12:46,600 I'm not going to be able to live in my full potential. 183 00:12:46,600 --> 00:12:49,900 And so you're seeing these people who don't know how to deal with stress. 184 00:12:49,900 --> 00:12:51,400 And number one, they're overweight. 185 00:12:51,400 --> 00:12:52,600 They're metabolically unfit. 186 00:12:52,600 --> 00:12:55,800 Nine out of 10 Americans are metabolically instead of two out of three Americans 187 00:12:55,800 --> 00:12:58,400 have an unsafe elevation and blood pressure. 188 00:12:58,400 --> 00:13:01,700 And so again, if you, if you lost the ability to produce nitric oxide, 189 00:13:01,700 --> 00:13:03,100 you can't dilate blood vessels. 190 00:13:03,100 --> 00:13:04,100 You become hypertensive. 191 00:13:04,100 --> 00:13:05,600 You can't get glucose into the cell. 192 00:13:05,600 --> 00:13:09,700 You develop insulin resistance and then platelets become hyperactive. 193 00:13:09,700 --> 00:13:12,200 Your blood vessels start to clog up and the plates, 194 00:13:12,200 --> 00:13:15,500 platelets are the plaque ruptures and platelets clot. 195 00:13:15,500 --> 00:13:17,500 And you develop a heart attack or stroke. 196 00:13:17,500 --> 00:13:22,500 So that entire sequence of a vent which puts people at risk for heart attack and stroke 197 00:13:22,500 --> 00:13:24,600 because they have underlying cardiovascular disease 198 00:13:24,600 --> 00:13:28,500 that may be symptomatic or asymptomatic in some cases. 199 00:13:28,500 --> 00:13:32,600 You know, can all be mitigated by focusing on nitric oxide. 200 00:13:32,600 --> 00:13:35,100 Stop doing the things that disrupts its production 201 00:13:35,100 --> 00:13:38,200 and then start doing the things that we've proven to clinically activate 202 00:13:38,200 --> 00:13:42,200 and stimulate and restore nitric oxide production. 203 00:13:42,200 --> 00:13:42,700 I love it. 204 00:13:42,700 --> 00:13:45,600 I think of, and maybe this is just how my brain works. 205 00:13:45,600 --> 00:13:48,100 I think of my health like a hamster wheel. 206 00:13:48,100 --> 00:13:51,700 And each one of those reels is something like sleep, 207 00:13:51,700 --> 00:13:54,700 a nutrition, an exercise. 208 00:13:54,700 --> 00:14:00,300 I'm curious about, you know, what are professionals doing wrong? 209 00:14:00,300 --> 00:14:01,700 I know it's not just sleep. 210 00:14:01,700 --> 00:14:03,100 It's just not diet. 211 00:14:03,100 --> 00:14:06,300 Like where are we missing the mark? 212 00:14:06,300 --> 00:14:11,300 And where is the real room for improvement today? 213 00:14:11,300 --> 00:14:16,400 As far as lifestyle, the lifestyle equation, I guess is what I'll call it. 214 00:14:16,400 --> 00:14:20,300 This episode sponsor is a couple I absolutely love. 215 00:14:20,300 --> 00:14:26,000 David and Alexis Kiwi, they help power couples be successful at home 216 00:14:26,000 --> 00:14:27,800 just like they are at work. 217 00:14:27,800 --> 00:14:29,900 If you're crushing it in the business world, 218 00:14:29,900 --> 00:14:32,500 but quietly disconnected from your spouse, 219 00:14:32,500 --> 00:14:33,800 you're not alone. 220 00:14:33,800 --> 00:14:36,900 Check them out at David and Alexis Kiwi.org. 221 00:14:36,900 --> 00:14:40,200 They have spent years creating a simple tool set 222 00:14:40,200 --> 00:14:42,200 that will help you save your marriage. 223 00:14:42,200 --> 00:14:48,400 Don't forget to use code executive one to save $500 off their six-week coaching programs. 224 00:14:48,400 --> 00:14:56,200 David and Alexis Kiwi.org code executive one. 225 00:14:56,200 --> 00:14:59,000 Well, I think the American lifestyle is probably the most, 226 00:14:59,000 --> 00:15:00,800 why not probably it is the most unhealthy. 227 00:15:00,800 --> 00:15:06,100 I mean, we have the sickest people on the planet with the most advanced nation on Earth. 228 00:15:06,100 --> 00:15:07,600 And yet we have the sickest people. 229 00:15:07,600 --> 00:15:11,600 So we may not be living longer, I think, 230 00:15:11,600 --> 00:15:14,400 but the quality of the life, even extending life. 231 00:15:14,400 --> 00:15:17,300 And I think probably over the past 30, 40 years I've seen data 232 00:15:17,300 --> 00:15:19,200 where we're actually not living longer. 233 00:15:19,200 --> 00:15:20,800 In fact, this may be the first generation 234 00:15:20,800 --> 00:15:22,600 where we're not going to live, you know, 235 00:15:22,600 --> 00:15:24,200 where our kids aren't going to live longer than us. 236 00:15:24,200 --> 00:15:28,100 We're on a negative decline here. 237 00:15:28,100 --> 00:15:29,400 But I think it's, there's a look, 238 00:15:29,400 --> 00:15:33,200 we live in a toxic world, the food we eat is depleted of any nutrients. 239 00:15:33,200 --> 00:15:36,600 We're exposed to toxins and then we're, 240 00:15:36,600 --> 00:15:40,600 we don't get enough exercise, we stress too much, we don't get enough sleep. 241 00:15:40,600 --> 00:15:42,200 And everything that I've just talked about, 242 00:15:42,200 --> 00:15:45,000 depletes the body's ability to produce micro-coxid, 243 00:15:45,000 --> 00:15:49,000 and that's the earliest event in the onset progression of chronic disease. 244 00:15:49,000 --> 00:15:50,800 But you know, it starts in the mouth, 245 00:15:50,800 --> 00:15:52,200 you know, fluoride in your toothpaste. 246 00:15:52,200 --> 00:15:54,600 Anything that kills the microbiome, 247 00:15:54,600 --> 00:15:57,200 two out of three Americans use mouthwash every day, 248 00:15:57,200 --> 00:16:00,000 destroying the microbiome, the oral microbiome, 249 00:16:00,000 --> 00:16:01,600 decreasing nitric oxide production, 250 00:16:01,600 --> 00:16:03,400 we see their blood pressure do level. 251 00:16:03,400 --> 00:16:05,400 And then things like an acids, you know, 252 00:16:05,400 --> 00:16:07,400 people who are eating, especially these executives, 253 00:16:07,400 --> 00:16:10,000 they eat on the run, develop heartburn, 254 00:16:10,000 --> 00:16:12,000 take proton puppet inhibitors, your polysac, 255 00:16:12,000 --> 00:16:13,800 your privacy, your nexium, 256 00:16:13,800 --> 00:16:15,400 and now those drugs completely shut down 257 00:16:15,400 --> 00:16:16,600 nitric oxide production, 258 00:16:16,600 --> 00:16:19,800 leading to a 40% increase in heart attack, stroke, and Alzheimer's. 259 00:16:19,800 --> 00:16:25,000 That's indisputable data that was published over the past five years. 260 00:16:25,000 --> 00:16:28,400 And then sedentary lifestyle, too much stress, 261 00:16:28,400 --> 00:16:29,900 not getting enough sleep. 262 00:16:29,900 --> 00:16:32,400 I mean, it's a recipe for disaster. 263 00:16:32,400 --> 00:16:35,200 So for me personally, I've made a conscious decision. 264 00:16:35,200 --> 00:16:38,000 I don't worry about things I can't control. 265 00:16:38,000 --> 00:16:40,900 And then I try to get a good seven, eight hours, 266 00:16:40,900 --> 00:16:42,300 nine hours is optimal for me. 267 00:16:42,300 --> 00:16:44,000 If I can get eight hours, I'm pretty good. 268 00:16:44,000 --> 00:16:46,000 But you know, wake up in the morning, 269 00:16:46,000 --> 00:16:47,800 start my day in prayer and gratitude, 270 00:16:47,800 --> 00:16:50,900 and you know, I'm in infrared sauna to detox, 271 00:16:50,900 --> 00:16:52,400 develop my strategy for the day, 272 00:16:52,400 --> 00:16:54,800 make sure that my day is completely planned. 273 00:16:54,800 --> 00:16:57,300 And I go about my day, 274 00:16:57,300 --> 00:16:59,400 but that's every day, you know, my creature have had it, 275 00:16:59,400 --> 00:17:05,400 but I do those same things and it hasn't felt me in 51 years now. 276 00:17:05,400 --> 00:17:07,200 I love it. 277 00:17:07,200 --> 00:17:12,400 And I love that you mentioned that because I think that's such an important, 278 00:17:12,400 --> 00:17:18,200 man, it's an important nugget because most busy executives, 279 00:17:18,200 --> 00:17:22,200 they wake up, they grab their phone, they react right away. 280 00:17:22,200 --> 00:17:26,600 Every single day, it's like, I have 20 emails, I have a global company, 281 00:17:26,600 --> 00:17:30,100 you know, I got to hit this time zone first before they go to bed. 282 00:17:30,100 --> 00:17:32,100 And so I love what you said. 283 00:17:32,100 --> 00:17:38,100 I just have to reiterate that because I started that practice. 284 00:17:38,100 --> 00:17:44,800 I would say about five years ago where I wake up without my phone, 285 00:17:44,800 --> 00:17:47,900 I lay in bed, I work my plan, 286 00:17:47,900 --> 00:17:49,900 I set and gratitude in prayer, 287 00:17:49,900 --> 00:17:55,700 exercise, I work my day versus my day working me. 288 00:17:55,700 --> 00:17:59,700 And I find that I'm less stressed. 289 00:17:59,700 --> 00:18:04,500 Now, flipping that upside down when I travel for work, 290 00:18:04,500 --> 00:18:07,300 and I'm away from my process, 291 00:18:07,300 --> 00:18:11,700 I'm waking up and I'm on my phone, I'm reacting to the day, 292 00:18:11,700 --> 00:18:15,500 I'm eating more, I'm sleeping less, I may be drinking more. 293 00:18:15,500 --> 00:18:18,700 And so I think there's so much wisdom behind that, 294 00:18:18,700 --> 00:18:21,000 really working your day, 295 00:18:21,000 --> 00:18:23,500 getting it organized, setting and gratitude, 296 00:18:23,500 --> 00:18:26,800 like I do three things I need to accomplish today, 297 00:18:26,800 --> 00:18:28,800 three, not 500, 298 00:18:28,800 --> 00:18:31,800 and three things I'm grateful for. 299 00:18:31,800 --> 00:18:35,300 And simple things like eight hours of sleep, 300 00:18:35,300 --> 00:18:38,300 or when my husband brings me morning coffee, 301 00:18:38,300 --> 00:18:41,500 I'm always grateful for that when I don't even have to ask. 302 00:18:41,500 --> 00:18:45,000 And so I think there's so much beauty in that, 303 00:18:45,000 --> 00:18:48,100 it's simple but it's so true. 304 00:18:48,100 --> 00:18:50,900 So I want to pivot a little bit and, 305 00:18:50,900 --> 00:18:53,900 you know, biomarkers or everything these days. 306 00:18:53,900 --> 00:18:59,900 So are there any specific biomarkers at home tests? 307 00:18:59,900 --> 00:19:03,400 Like what's the secret on where executives 308 00:19:03,400 --> 00:19:08,500 and what executives should be monitoring to track their longevity? 309 00:19:08,500 --> 00:19:11,800 Well, specifically as it relates to nitric oxide, 310 00:19:11,800 --> 00:19:12,900 we know they're biomarkers, 311 00:19:12,900 --> 00:19:15,900 they're symptoms that show up or manifest as a result 312 00:19:15,900 --> 00:19:17,500 of loss of micrococytal production. 313 00:19:17,500 --> 00:19:18,500 And there's a hierarchy. 314 00:19:18,500 --> 00:19:21,300 So number one, you start to develop a reptile dysfunction. 315 00:19:21,300 --> 00:19:24,100 Right, if you can't dilate the blood vessels of the sex organs, 316 00:19:24,100 --> 00:19:26,900 you can't get in gorge when that's both in men and women, 317 00:19:26,900 --> 00:19:27,700 for example. 318 00:19:27,700 --> 00:19:29,900 So we call that the canary and the coal mine. 319 00:19:29,900 --> 00:19:31,300 If you've got in the thevil dysfunction 320 00:19:31,300 --> 00:19:33,500 and the astrobed of the sex organs of the pelvic region, 321 00:19:33,500 --> 00:19:35,100 then you've got in the thevil dysfunction. 322 00:19:35,100 --> 00:19:36,800 It's a systemic disease. 323 00:19:36,800 --> 00:19:39,300 Number two, your blood pressure starts to go up. 324 00:19:39,300 --> 00:19:41,100 Because if you're not dilating the blood vessels 325 00:19:41,100 --> 00:19:42,600 through the production of nitric oxide, 326 00:19:42,600 --> 00:19:45,500 you've got that same volume of blood going through smaller pipes 327 00:19:45,500 --> 00:19:49,300 and simple laws of physics tell us the pressure has to come up. 328 00:19:49,300 --> 00:19:50,940 And so two out of three Americans have an unsafe 329 00:19:50,940 --> 00:19:52,600 elevation in blood pressure. 330 00:19:52,600 --> 00:19:55,100 Number three, you start to get insulin resistance 331 00:19:55,100 --> 00:19:58,300 because you need nitric oxide to get glucose into the cell 332 00:19:58,300 --> 00:20:01,600 when insulin binds to the insulin receptor. 333 00:20:01,600 --> 00:20:04,600 And nine out of 10 Americans are metabolically unfit. 334 00:20:04,600 --> 00:20:07,000 Number four, you start to develop exercise in tolerance. 335 00:20:07,000 --> 00:20:08,500 If you can't walk up a fight of stairs 336 00:20:08,500 --> 00:20:10,800 or do 20, 30 minutes of moderate physical exercise 337 00:20:10,800 --> 00:20:14,500 without getting winded and test chest tightening 338 00:20:14,500 --> 00:20:16,200 in that then your nitric oxide deficient. 339 00:20:16,200 --> 00:20:18,500 And then you start to lose your mental edge. 340 00:20:18,500 --> 00:20:20,100 You develop mild cognitive impairment. 341 00:20:20,100 --> 00:20:22,100 You're not as sharp as you were. 342 00:20:22,100 --> 00:20:24,900 You're making poor decisions as an executive. 343 00:20:24,900 --> 00:20:27,600 And eventually if not corrected, then let's dimension 344 00:20:27,600 --> 00:20:29,900 and eventually Alzheimer's. 345 00:20:29,900 --> 00:20:33,600 So those are the physical symptoms that we keep an eye on. 346 00:20:33,600 --> 00:20:35,600 In terms of biomarkers, blood biomarkers, 347 00:20:35,600 --> 00:20:38,300 we see see reactive protein go up. 348 00:20:38,300 --> 00:20:40,400 We see triglycerides go up. 349 00:20:40,400 --> 00:20:43,300 We see ferritin levels go up. 350 00:20:43,300 --> 00:20:45,900 And we see glucose and insulin on the rise. 351 00:20:45,900 --> 00:20:49,200 And so all of those metabolic biomarkers 352 00:20:49,200 --> 00:20:52,900 or biomarkers of inflammation cannot be corrected 353 00:20:52,900 --> 00:20:55,300 by restoring the natural production of nitric oxide. 354 00:20:55,300 --> 00:20:57,100 In fact, one of my patents is number two. 355 00:20:57,100 --> 00:21:00,000 My patent one is on a method of reducing inflammation. 356 00:21:00,000 --> 00:21:03,100 37% reduction in C-reactive protein after 30 days 357 00:21:03,100 --> 00:21:05,500 and the other is lowering triglycerides. 358 00:21:05,500 --> 00:21:08,100 27% reduction in triglycerides and patients 359 00:21:08,100 --> 00:21:10,800 who have triglycerides greater than 150. 360 00:21:10,800 --> 00:21:11,800 Just in 30 days. 361 00:21:11,800 --> 00:21:14,600 So if we're restoring nitric oxide production, 362 00:21:14,600 --> 00:21:17,400 we're balancing our metabolism, 363 00:21:17,400 --> 00:21:18,900 we're overcoming insulin resistance, 364 00:21:18,900 --> 00:21:20,800 we're normalizing blood flow, blood pressure, 365 00:21:20,800 --> 00:21:23,200 reducing inflammation, I mean all the good things 366 00:21:23,200 --> 00:21:28,600 that we look for in longevity and human optimization. 367 00:21:28,600 --> 00:21:29,500 It's interesting. 368 00:21:29,500 --> 00:21:31,200 I think about inflammation. 369 00:21:31,200 --> 00:21:33,800 And I think, I mean, I'm no doctor. 370 00:21:33,800 --> 00:21:35,600 I'll have to ask you these questions. 371 00:21:35,600 --> 00:21:39,300 But it seems like most of the disease is all centered 372 00:21:39,300 --> 00:21:41,300 around inflammation in our body. 373 00:21:41,300 --> 00:21:44,700 I think of all the, you know, even acne, right? 374 00:21:44,700 --> 00:21:49,000 Even all of them that I can think of as we're talking, 375 00:21:49,000 --> 00:21:51,300 they all seem to come from inflammation. 376 00:21:51,300 --> 00:21:55,000 So you'd think if you can decrease the inflammation, 377 00:21:55,000 --> 00:21:59,100 you could easily increase your health, I would think. 378 00:21:59,100 --> 00:22:00,000 For sure. 379 00:22:00,000 --> 00:22:02,600 Now, like inflammation is necessary. 380 00:22:02,600 --> 00:22:05,400 And if we get an infection or we get a cut, 381 00:22:05,400 --> 00:22:08,600 you know, we need that acute inflammatory response to go 382 00:22:08,600 --> 00:22:12,200 and, you know, number one, isolate that source of infection 383 00:22:12,200 --> 00:22:14,200 and then bring our immune cells in and then repair 384 00:22:14,200 --> 00:22:15,200 and regenerate the tissue. 385 00:22:15,200 --> 00:22:19,600 All of that is controlled by an acute inflammatory response. 386 00:22:19,600 --> 00:22:22,200 It's bringing the fire trucks to the fire. 387 00:22:22,200 --> 00:22:23,300 We need that. 388 00:22:23,300 --> 00:22:28,100 Now, the problem is is when we have uncontrolled inflammation 389 00:22:28,100 --> 00:22:31,500 and that's the driver of, you know, chronic disease, 390 00:22:31,500 --> 00:22:33,000 all chronic disease. 391 00:22:33,000 --> 00:22:35,200 But, you know, all that can be explained by nitric oxide. 392 00:22:35,200 --> 00:22:36,800 So in that whole process, 393 00:22:36,800 --> 00:22:39,400 if we lose the production of nitric oxide, 394 00:22:39,400 --> 00:22:42,600 then if we get, you know, exposed to a virus or a bacterium 395 00:22:42,600 --> 00:22:44,600 or we have an injury, 396 00:22:44,600 --> 00:22:49,000 we don't have good mobilization of our immune cells to go 397 00:22:49,000 --> 00:22:50,800 because, you know, we've got, you know, 398 00:22:50,800 --> 00:22:53,700 if you order something on Amazon and the cargo is on the truck, 399 00:22:53,700 --> 00:22:55,300 but there's a traffic jam, you know, 400 00:22:55,300 --> 00:22:56,700 you're not going to deliver that cargo, 401 00:22:56,700 --> 00:22:59,700 which is the oxygen, the nutrients for that cell to do its job. 402 00:22:59,700 --> 00:23:01,700 So nitric oxide dilates those blood vessels, 403 00:23:01,700 --> 00:23:02,700 clears the traffic jam, 404 00:23:02,700 --> 00:23:04,800 so now you can get the immune cells to the side of infection 405 00:23:04,800 --> 00:23:07,400 or the side of injury in the body. 406 00:23:07,400 --> 00:23:09,900 And then we start to get oxidative stress. 407 00:23:09,900 --> 00:23:12,300 And then that's when the inflammation, 408 00:23:12,300 --> 00:23:15,000 inflammation is driven by a lot of oxygen radicals. 409 00:23:15,000 --> 00:23:17,200 And then our immune cells become confused 410 00:23:17,200 --> 00:23:19,000 and we develop immune dysfunction. 411 00:23:19,000 --> 00:23:22,000 But if we can just give nitric oxide and restore nitric oxide, 412 00:23:22,000 --> 00:23:23,200 we decrease inflammation, 413 00:23:23,200 --> 00:23:24,400 we inhibit oxidative stress 414 00:23:24,400 --> 00:23:26,200 and we correct the immune dysfunction 415 00:23:26,200 --> 00:23:28,800 that you see in every single chronic disease. 416 00:23:28,800 --> 00:23:31,400 And it doesn't matter if it's Alzheimer's, cardiovascular disease, 417 00:23:31,400 --> 00:23:33,600 autoimmune disease, kidney disease, 418 00:23:33,600 --> 00:23:36,000 pulmonary disease, liver disease, it's all the same. 419 00:23:36,000 --> 00:23:39,200 It's the hallmarks of chronic disease. 420 00:23:39,200 --> 00:23:41,600 Yeah, and I'm thinking, you know, 421 00:23:41,600 --> 00:23:45,200 I've had some discussions with my baby boomer friends 422 00:23:45,200 --> 00:23:47,200 and others and, you know, 423 00:23:47,200 --> 00:23:48,900 it seems like they have one thing 424 00:23:48,900 --> 00:23:52,000 and then they have another thing and then another thing. 425 00:23:52,000 --> 00:23:54,800 It's kind of like this chain reaction these days 426 00:23:54,800 --> 00:23:59,000 and they all seem like they're autoimmune diseases 427 00:23:59,000 --> 00:24:01,800 or issues and, you know, 428 00:24:01,800 --> 00:24:05,000 this pill needs that pill and that pill needs this pill 429 00:24:05,000 --> 00:24:06,900 and them together is, 430 00:24:06,900 --> 00:24:10,200 so how, like, if someone's out there 431 00:24:10,200 --> 00:24:14,000 and they're in that space where they had some of the issues 432 00:24:14,000 --> 00:24:15,600 that you're talking about, 433 00:24:15,600 --> 00:24:18,300 let's talk about what they can do 434 00:24:18,300 --> 00:24:21,700 and maybe the top three changes 435 00:24:21,700 --> 00:24:26,600 that somebody could make today to boost their nitric oxide levels. 436 00:24:26,600 --> 00:24:29,600 Well, that's, it's a very good question 437 00:24:29,600 --> 00:24:31,100 and it's a very well defined answer 438 00:24:31,100 --> 00:24:34,100 because we've been setting this for the past 25 years. 439 00:24:34,100 --> 00:24:37,000 So number one, you have to get rid of fluoride in your toothpaste 440 00:24:37,000 --> 00:24:40,800 and the other problem is 73% of the municipalities in the US 441 00:24:40,800 --> 00:24:43,000 put fluoride in the drinking water. 442 00:24:43,000 --> 00:24:43,900 And why do they do that? 443 00:24:43,900 --> 00:24:45,300 Well, because it's anti-bacteria, 444 00:24:45,300 --> 00:24:47,500 you want to kill the bacteria in the pipes 445 00:24:47,500 --> 00:24:50,600 that you're cooking in, you're drinking in the water 446 00:24:50,600 --> 00:24:51,800 and that you're even bathing in, 447 00:24:51,800 --> 00:24:53,200 but that fluoride is antiseptic. 448 00:24:53,200 --> 00:24:56,000 It kills the bacteria on your body, in your body. 449 00:24:56,000 --> 00:24:59,400 You drink it, it's in the foods that you're cooking in 450 00:24:59,400 --> 00:25:01,600 and it's shutting down your thyroid function. 451 00:25:01,600 --> 00:25:04,300 It's a neurotoxin and it's antiseptic. 452 00:25:04,300 --> 00:25:05,900 I mean, we have to give it a fluoride. 453 00:25:05,900 --> 00:25:09,500 Fluoride is a toxin that lowers IQ by as much as seven points 454 00:25:09,500 --> 00:25:11,000 in young kids. 455 00:25:11,000 --> 00:25:13,300 So that's number one, switch your toothpaste. 456 00:25:13,300 --> 00:25:18,400 I developed a fluoride-free, really nitric oxide, biome, targeted 457 00:25:18,400 --> 00:25:19,800 toothpaste called cardio smile, 458 00:25:19,800 --> 00:25:21,600 and it's changing people's lives. 459 00:25:21,600 --> 00:25:25,100 Number two are antiseptic mouthwash, 460 00:25:25,100 --> 00:25:26,900 two out of three Americans get up every morning 461 00:25:26,900 --> 00:25:30,400 and they're on a atomic bomb in their mouth killing all the bacteria 462 00:25:30,400 --> 00:25:31,900 creating a sterile environment. 463 00:25:31,900 --> 00:25:34,500 We've shown that that shuts down nitric oxide production, 464 00:25:34,500 --> 00:25:35,600 their blood pressure goes up, 465 00:25:35,600 --> 00:25:38,100 they lose the protective benefits of the exercise. 466 00:25:38,100 --> 00:25:40,500 And then third is get off an acids. 467 00:25:40,500 --> 00:25:42,500 Autoimmune disease is caused 468 00:25:42,500 --> 00:25:44,700 from insufficient stomach acid production 469 00:25:44,700 --> 00:25:46,900 because we need stomach acid to break down proteins 470 00:25:46,900 --> 00:25:48,500 into amino acids. 471 00:25:48,500 --> 00:25:50,300 If we don't have stomach acid, 472 00:25:50,300 --> 00:25:52,500 we're absorbing undigested peptide fragments 473 00:25:52,500 --> 00:25:53,700 across the lining of the gut 474 00:25:53,700 --> 00:25:56,200 and our body develops an antibody response 475 00:25:56,200 --> 00:25:57,300 from immune reaction to it. 476 00:25:57,300 --> 00:25:59,100 And we develop foodborne allergies, 477 00:25:59,100 --> 00:26:00,600 immune dysfunction, 478 00:26:00,600 --> 00:26:02,600 and that's autoimmune disease. 479 00:26:02,600 --> 00:26:06,000 And many doctors call it idiopathic fibromyalgia, 480 00:26:06,000 --> 00:26:08,400 but you know, are some type of syndrome 481 00:26:08,400 --> 00:26:09,700 that they can now treat with a drug. 482 00:26:09,700 --> 00:26:11,100 But the problem is, you know, 483 00:26:11,100 --> 00:26:13,500 use the hamster wheel as a metaphor. 484 00:26:13,500 --> 00:26:16,200 And I think that's the metaphor of big forma 485 00:26:16,200 --> 00:26:19,100 because you know, big form is a for-profit business. 486 00:26:19,100 --> 00:26:21,800 It's the biggest industry in the history of the world. 487 00:26:21,800 --> 00:26:24,600 It's multi-trillion dollar annualized industry. 488 00:26:24,600 --> 00:26:27,000 They're the best at it because they get you on that hamster wheel 489 00:26:27,000 --> 00:26:28,200 and they treat you with one drug. 490 00:26:28,200 --> 00:26:29,500 That drug causes a side effect. 491 00:26:29,500 --> 00:26:31,000 They get them out treat with another drug. 492 00:26:31,000 --> 00:26:33,200 And that drug causes a side effect. 493 00:26:33,200 --> 00:26:35,200 And you know, in for-profit business, 494 00:26:35,200 --> 00:26:37,800 the number one rule is get as many customers as you can 495 00:26:37,800 --> 00:26:40,200 and keep them as long as you can. 496 00:26:40,200 --> 00:26:43,000 And big form is the best in the business of them. 497 00:26:43,000 --> 00:26:44,300 To our own demise, right? 498 00:26:44,300 --> 00:26:47,300 It's not, it's very healthy financially, 499 00:26:47,300 --> 00:26:50,200 but it's the most unhealthy thing for us as humans. 500 00:26:50,200 --> 00:26:52,000 Yeah, I agree. 501 00:26:52,000 --> 00:26:54,900 I've seen people ping pong around to doctors 502 00:26:54,900 --> 00:26:58,600 with different medication and then they die shortly after. 503 00:26:58,600 --> 00:27:01,200 And so I often wonder what could we- 504 00:27:01,200 --> 00:27:03,100 No, I tell people, fire your doctor. 505 00:27:03,100 --> 00:27:05,200 Look, if you took your car to a mechanic 506 00:27:05,200 --> 00:27:07,900 and it kept breaking down, that's very simple. 507 00:27:07,900 --> 00:27:11,200 You would fire that mechanic because he has not fixed the problem. 508 00:27:11,200 --> 00:27:13,700 If you've got a doctor and you still feeling bad 509 00:27:13,700 --> 00:27:14,700 and every time you go back, 510 00:27:14,700 --> 00:27:16,600 you put you on different medication 511 00:27:16,600 --> 00:27:19,900 or he's not making you better, fire that doctor 512 00:27:19,900 --> 00:27:22,900 and go find somebody who understands your symptoms 513 00:27:22,900 --> 00:27:25,000 who can take the time to listen to you, 514 00:27:25,000 --> 00:27:27,300 do an inventory of the drug therapy you're taking 515 00:27:27,300 --> 00:27:30,500 and talk about, how do we get people off drugs? 516 00:27:30,500 --> 00:27:32,300 Because most doctors like, okay, if that don't work 517 00:27:32,300 --> 00:27:33,300 or you don't get better, come back, 518 00:27:33,300 --> 00:27:35,200 I'm gonna put you around the drug. 519 00:27:35,200 --> 00:27:36,700 And then you look up, you're 50 years old 520 00:27:36,700 --> 00:27:38,600 and most people are on half a dozen, 521 00:27:38,600 --> 00:27:41,500 sometimes a dozen, 18 different medications 522 00:27:41,500 --> 00:27:44,700 and they wonder why they feel bad. 523 00:27:44,700 --> 00:27:45,500 Yeah, so true. 524 00:27:45,500 --> 00:27:47,500 I'm thinking about my own family. 525 00:27:47,500 --> 00:27:49,500 The healthiest people in my family 526 00:27:49,500 --> 00:27:52,700 don't see a doctor, but occasionally. 527 00:27:52,700 --> 00:27:57,200 And they aren't on any medication. 528 00:27:57,200 --> 00:28:00,200 So we've solved that. 529 00:28:00,200 --> 00:28:04,000 And I'm thinking in my brain as a traveling executive. 530 00:28:04,000 --> 00:28:08,300 You know, I've stressed and I over-trained sometimes 531 00:28:08,300 --> 00:28:10,800 because I'm an athlete at heart. 532 00:28:10,800 --> 00:28:15,300 I'm curious how nitric oxide effects are, 533 00:28:15,300 --> 00:28:16,800 like, how to travel stress 534 00:28:16,800 --> 00:28:20,100 and overtraining effect nitric oxide levels 535 00:28:20,100 --> 00:28:22,200 and long-term health? 536 00:28:22,200 --> 00:28:23,700 Well, it's all about recovering. 537 00:28:23,700 --> 00:28:26,700 So number one, it's about giving them out of connery 538 00:28:26,700 --> 00:28:29,000 and what they need and improving the efficiency 539 00:28:29,000 --> 00:28:30,500 of mitochondria. 540 00:28:30,500 --> 00:28:34,500 So if you overtrain, you know, it's all about, 541 00:28:34,500 --> 00:28:36,700 in terms of recovery, it's lactic acid buildup. 542 00:28:36,700 --> 00:28:40,300 So when you, when you, your mitochondria aren't functional, 543 00:28:40,300 --> 00:28:41,300 they start to get into this. 544 00:28:41,300 --> 00:28:43,400 When you push past that anaerobic threshold, 545 00:28:43,400 --> 00:28:46,200 then you start to get lactic acid production. 546 00:28:46,200 --> 00:28:49,200 That makes muscle soar you over-training and you recover slowly. 547 00:28:49,200 --> 00:28:51,000 But if we're optimized in nitric oxide, 548 00:28:51,000 --> 00:28:53,160 we're basically extending that oxygen 549 00:28:53,160 --> 00:28:54,600 gradient in the tissue. 550 00:28:54,600 --> 00:28:56,900 Nitric oxide leads to mitochondrial biogenesis, 551 00:28:56,900 --> 00:28:59,300 so we're having more mitochondria per cell 552 00:28:59,300 --> 00:29:02,400 generate more energy with less oxygen. 553 00:29:02,400 --> 00:29:04,300 So you don't get the lactic acid buildup 554 00:29:04,300 --> 00:29:05,400 and you recover better. 555 00:29:05,400 --> 00:29:07,400 Number one, you're going to get a much better workout. 556 00:29:07,400 --> 00:29:09,500 It's going to be harder to overtrain 557 00:29:09,500 --> 00:29:12,000 because you become more efficient at creating 558 00:29:12,000 --> 00:29:14,000 cellot energy with the oxygen. 559 00:29:14,000 --> 00:29:16,600 And then you're just going to get good circulation, 560 00:29:16,600 --> 00:29:18,900 good blood flow, adequate oxygen delivery. 561 00:29:18,900 --> 00:29:20,640 But without nitric oxide, you're not going to get 562 00:29:20,640 --> 00:29:22,600 adequate oxygen delivery, you're not going to get adequate 563 00:29:22,600 --> 00:29:27,700 ATP production from that oxygen. 564 00:29:27,700 --> 00:29:32,400 And you're going to overtrain and you're going to have poor recovery. 565 00:29:32,400 --> 00:29:33,200 I love that. 566 00:29:33,200 --> 00:29:35,900 I always tell myself after I travel, Melissa, 567 00:29:35,900 --> 00:29:38,600 rigorous self-care, rigorous self-care, 568 00:29:38,600 --> 00:29:40,600 rest in relaxation. 569 00:29:40,600 --> 00:29:42,000 So, you know, look, it's tough. 570 00:29:42,000 --> 00:29:44,600 You know, last year I traveled 160,000 air miles 571 00:29:44,600 --> 00:29:47,100 and I spent over 200 nights in a hotel. 572 00:29:47,100 --> 00:29:50,100 But you know, rather than when you go and when I land, 573 00:29:50,100 --> 00:29:53,200 no matter where I am in the world, I go to the gym. 574 00:29:53,200 --> 00:29:56,600 Because if I'm traveling, you know, 14, 16 hours across the world 575 00:29:56,600 --> 00:29:59,800 or four hours or three hours, you know, in the US, 576 00:29:59,800 --> 00:30:04,000 you know, human nature is to go take a nap and rest, right? 577 00:30:04,000 --> 00:30:06,600 But I have enough discipline out of where 578 00:30:06,600 --> 00:30:09,700 because I know if I do that, it's going to ruin my entire day. 579 00:30:09,700 --> 00:30:11,600 So I immediately go to the gym and I usually stay 580 00:30:11,600 --> 00:30:14,800 in places where there's an infrared sauna or a sauna 581 00:30:14,800 --> 00:30:18,500 where I can train, I can do cardio, I can sit in a sauna 582 00:30:18,500 --> 00:30:23,200 and detox and spend time alone and, you know, in prayer 583 00:30:23,200 --> 00:30:26,500 and developing my plan for the day. 584 00:30:26,500 --> 00:30:28,500 But then, you know, you try to eat healthy 585 00:30:28,500 --> 00:30:30,800 but sometimes it's hard to eat healthy. 586 00:30:30,800 --> 00:30:33,700 So traveling a lot is, you know, it's taxing, 587 00:30:33,700 --> 00:30:36,100 but, you know, you have to have the discipline 588 00:30:36,100 --> 00:30:37,700 to make the right decisions. 589 00:30:37,700 --> 00:30:41,400 You know, you are either one could survive this. 590 00:30:41,400 --> 00:30:42,400 Yeah, I agree. 591 00:30:42,400 --> 00:30:46,900 I think that's discipline's key to all the things we want in our life. 592 00:30:46,900 --> 00:30:50,500 Tell me what your, what breakthroughs are you most excited 593 00:30:50,500 --> 00:30:55,900 about right now as it relates to nitric oxide? 594 00:30:55,900 --> 00:30:58,400 You know, I'm excited about our drug therapy program. 595 00:30:58,400 --> 00:31:01,100 You know, we've had products, consumer products on the market 596 00:31:01,100 --> 00:31:03,200 for a number of years now and, you know, 597 00:31:03,200 --> 00:31:06,100 with the market leaders, our products produce nitric oxide 598 00:31:06,100 --> 00:31:09,300 and, you know, we're certainly the market leaders in that. 599 00:31:09,300 --> 00:31:12,800 But for me, getting in this field 25 years ago, 600 00:31:12,800 --> 00:31:16,500 my whole purpose was to understand the mechanism of disease 601 00:31:16,500 --> 00:31:19,300 to the extent that you can develop rational therapies. 602 00:31:19,300 --> 00:31:21,000 And so even though our consumer products 603 00:31:21,000 --> 00:31:23,900 are highly successful, highly efficacious, 604 00:31:23,900 --> 00:31:25,300 you know, being an academia, 605 00:31:25,300 --> 00:31:27,100 being a professor of medicine at a medical school 606 00:31:27,100 --> 00:31:27,900 for a number of years, 607 00:31:27,900 --> 00:31:31,200 our whole mission was to develop a double drug therapies, 608 00:31:31,200 --> 00:31:33,500 safe and affect them drugs. 609 00:31:33,500 --> 00:31:35,000 So we've got a drug that we've developed 610 00:31:35,000 --> 00:31:38,700 in nitric oxide releasing drug for a Schema Card disease, 611 00:31:38,700 --> 00:31:41,600 which I think is going to transform the treatment 612 00:31:41,600 --> 00:31:44,300 and care of patients with a Schema Card disease. 613 00:31:44,300 --> 00:31:47,200 Number two, we've got a drug we're developing for Alzheimer's. 614 00:31:47,200 --> 00:31:49,400 And I'm absolutely convinced that nitric oxide 615 00:31:49,400 --> 00:31:52,100 will cure and eradicate Alzheimer's. 616 00:31:52,100 --> 00:31:53,300 And we're developing that. 617 00:31:53,300 --> 00:31:54,300 We've met with the FDA. 618 00:31:54,300 --> 00:31:56,300 We're hopefully designed those trials 619 00:31:56,300 --> 00:31:59,000 and get that, you know, this clinical trial started here 620 00:31:59,000 --> 00:32:01,000 in the next two years or so. 621 00:32:01,000 --> 00:32:03,500 And then we make a topical drug for diabetic ulcers, 622 00:32:03,500 --> 00:32:04,800 non-healing wounds. 623 00:32:04,800 --> 00:32:07,600 In 65,000 Americans die in nursing homes every year 624 00:32:07,600 --> 00:32:08,900 from wounds, non-healing wounds 625 00:32:08,900 --> 00:32:11,100 that get infected in the dive substances. 626 00:32:11,100 --> 00:32:14,600 And to me, that's unacceptable because nitric oxide, 627 00:32:14,600 --> 00:32:16,600 we haven't seen a wound that we haven't been able 628 00:32:16,600 --> 00:32:19,100 to heal with nitric oxide. 629 00:32:19,100 --> 00:32:21,100 And then, you know, Alzheimer's, again, 630 00:32:21,100 --> 00:32:24,400 it's correcting the root cause of dementia 631 00:32:24,400 --> 00:32:28,100 in Alzheimer's, which is overcoming the vascular 632 00:32:28,100 --> 00:32:30,300 and the metabolic phenotypes 633 00:32:30,300 --> 00:32:33,700 of mod cognitive impairment, dementia in Alzheimer's. 634 00:32:33,700 --> 00:32:36,600 So that's what, you know, gets me up every day motivated 635 00:32:36,600 --> 00:32:39,400 to make sure that, you know, we accomplish this 636 00:32:39,400 --> 00:32:42,400 because when we do this, when we get these drugs on the market, 637 00:32:42,400 --> 00:32:46,400 it's gonna change the world and health here's gonna be better for it 638 00:32:46,400 --> 00:32:48,200 because number one, the drugs are safe 639 00:32:48,200 --> 00:32:51,100 because what we do isn't pharmacology. 640 00:32:51,100 --> 00:32:52,800 We're not making synthetic compounds 641 00:32:52,800 --> 00:32:54,900 that are in him about chemical reactions, 642 00:32:54,900 --> 00:32:56,900 which is what most drugs are. 643 00:32:56,900 --> 00:32:59,900 We utilize the principles of restorative physiology. 644 00:32:59,900 --> 00:33:03,000 We give the body what it needs, the body heals itself. 645 00:33:03,000 --> 00:33:05,000 And so, there is no safety issue 646 00:33:05,000 --> 00:33:07,400 because this is an actually produced molecule. 647 00:33:07,400 --> 00:33:09,900 We're just giving back and actually produce molecules. 648 00:33:09,900 --> 00:33:11,800 So we don't worry about safety. 649 00:33:11,800 --> 00:33:14,200 Obviously, the doses we're given is extremely safe. 650 00:33:14,200 --> 00:33:16,700 So we just gotta dial in the right amount of nitric oxide 651 00:33:16,700 --> 00:33:20,200 for each indication and then we'll change the world. 652 00:33:20,200 --> 00:33:23,800 And you know, that's what I'm excited about. 653 00:33:23,800 --> 00:33:24,600 - I love it. 654 00:33:24,600 --> 00:33:28,500 So if you could create a longevity stack for executives, 655 00:33:28,500 --> 00:33:30,600 what would that look like? 656 00:33:30,600 --> 00:33:33,200 - Well, all I know is what works for me. 657 00:33:33,200 --> 00:33:35,200 And so I'll tell you what I do. 658 00:33:35,200 --> 00:33:37,800 You have to get sleep. 659 00:33:37,800 --> 00:33:39,800 If you don't get good night's sleep 660 00:33:39,800 --> 00:33:41,900 and you wake up rested and ready to go, 661 00:33:41,900 --> 00:33:43,600 then nothing else matters. 662 00:33:43,600 --> 00:33:45,800 So sleep, sleep is key. 663 00:33:45,800 --> 00:33:48,100 You know, for me, six to eight hours as I deal, 664 00:33:48,100 --> 00:33:49,700 I have to get at least six hours of sleep 665 00:33:49,700 --> 00:33:53,000 or I'm not top of my game. 666 00:33:53,000 --> 00:33:54,900 And then make time. 667 00:33:54,900 --> 00:33:57,800 If you wait till you have time to do these things, 668 00:33:57,800 --> 00:33:58,800 you'll never have time. 669 00:33:58,800 --> 00:34:00,000 So what I have to do is make time. 670 00:34:00,000 --> 00:34:01,300 Similar to you. 671 00:34:01,300 --> 00:34:03,700 Similar morning, I wake up really early 672 00:34:03,700 --> 00:34:07,600 because if my work day starts at 7 30 or 8, 673 00:34:07,600 --> 00:34:10,700 I've got to get up at 5 because I've got three hours of stuff. 674 00:34:10,700 --> 00:34:12,000 I have to get done. 675 00:34:12,000 --> 00:34:15,700 I sit in a sauna for 30 minutes and 170 degrees. 676 00:34:15,700 --> 00:34:16,700 I open my hollow app. 677 00:34:16,700 --> 00:34:19,400 I read scripts, try to do prayer and start my day. 678 00:34:19,400 --> 00:34:20,600 What's my strategy? 679 00:34:20,600 --> 00:34:22,900 What I'm going to do and I plan it out. 680 00:34:22,900 --> 00:34:27,200 And then typically I'll sometimes I'll go in a cold plunge 681 00:34:27,200 --> 00:34:31,700 so I'll go from 170 degrees to 37 degrees for three minutes. 682 00:34:31,700 --> 00:34:33,800 And then I watch the sun come up. 683 00:34:33,800 --> 00:34:36,800 And that resets your circadian rhythm. 684 00:34:36,800 --> 00:34:39,200 I walk barefoot on the ground to get electrons 685 00:34:39,200 --> 00:34:41,500 to this whole concept of grounding. 686 00:34:41,500 --> 00:34:43,500 I do an 18 hour fast every day. 687 00:34:43,500 --> 00:34:46,500 That completely changes your metabolism. 688 00:34:46,500 --> 00:34:49,500 Eat my last meal at six and typically try not to eat till 689 00:34:49,500 --> 00:34:50,600 noon the next day. 690 00:34:50,600 --> 00:34:52,400 You know, obviously that's difficult sometimes 691 00:34:52,400 --> 00:34:54,300 because of which time zone I mean. 692 00:34:54,300 --> 00:34:56,600 But and then I exercise. 693 00:34:56,600 --> 00:34:59,400 You know wake up every morning and I exercise. 694 00:34:59,400 --> 00:35:01,100 I take my nitric oxide products. 695 00:35:01,100 --> 00:35:06,000 I know always at least do a hundred pushups and a hundred squats 696 00:35:06,000 --> 00:35:07,100 every day. 697 00:35:07,100 --> 00:35:08,600 Then sometimes I'll go to the gym. 698 00:35:08,600 --> 00:35:10,700 But you know, those are the must. 699 00:35:10,700 --> 00:35:13,600 Those are the you know, the non-negotiables. 700 00:35:13,600 --> 00:35:15,400 And it works for me. 701 00:35:15,400 --> 00:35:18,800 You know, I travel all over the world and you know, 702 00:35:18,800 --> 00:35:22,000 gone a lot, you know, been an enormous stress. 703 00:35:22,000 --> 00:35:24,200 I've been sued by competitors. 704 00:35:24,200 --> 00:35:28,300 You know, the stresses and the pressures of leading 705 00:35:28,300 --> 00:35:34,300 a global multimillion dollar organization is, 706 00:35:34,300 --> 00:35:36,300 you know, it's not for the faint of heart. 707 00:35:36,300 --> 00:35:40,900 So you have to you have to be fit mentally fit spiritually fit 708 00:35:40,900 --> 00:35:44,200 and physically fit to to rise to the challenge every day. 709 00:35:44,200 --> 00:35:46,400 I love it. 710 00:35:46,400 --> 00:35:48,800 Now if you could tell you're I love this question. 711 00:35:48,800 --> 00:35:50,400 I'm I have to ask it for you. 712 00:35:50,400 --> 00:35:54,700 If you could tell your younger self one thing about health and 713 00:35:54,700 --> 00:35:56,200 success, what would it be? 714 00:35:56,200 --> 00:36:01,800 Well, the younger self, you know, we got to avoid sugar. 715 00:36:01,800 --> 00:36:02,800 Sugar's a toxin. 716 00:36:02,800 --> 00:36:03,800 Sugar's the enemy. 717 00:36:03,800 --> 00:36:04,800 Sugar's the poison. 718 00:36:04,800 --> 00:36:09,800 So, you know, anything that leads to an increase in blood sugar 719 00:36:09,800 --> 00:36:13,500 is extremely damaging and is going to, you know, 720 00:36:13,500 --> 00:36:15,400 shorten your life, shorten your health span. 721 00:36:15,400 --> 00:36:19,000 You know, I got away with it early on because when we grew up, 722 00:36:19,000 --> 00:36:20,600 we were fit. We were outside running. 723 00:36:20,600 --> 00:36:24,000 And so if you're burning those calories and utilizing that 724 00:36:24,000 --> 00:36:26,600 and burning it, then it's not stored as fat. 725 00:36:26,600 --> 00:36:30,000 And if you consume sugar, then, you know, you kind of dampen 726 00:36:30,000 --> 00:36:32,000 that that glucose tolerance to that curve. 727 00:36:32,000 --> 00:36:33,200 And so your body takes it in. 728 00:36:33,200 --> 00:36:35,200 You don't store this fat. 729 00:36:35,200 --> 00:36:38,900 But, you know, for the average American who's again, 730 00:36:38,900 --> 00:36:43,300 metabolically unfit overweight, hypertensive, you know, 731 00:36:43,300 --> 00:36:46,100 just simply eliminating sugar and staying active. 732 00:36:46,100 --> 00:36:50,400 But, you know, 18 hour fast, balanced diet and moderation, 733 00:36:50,400 --> 00:36:53,600 elimination of sugar or, you know, high glycemic index foods 734 00:36:53,600 --> 00:36:56,100 is really a bit of gain change. 735 00:36:56,100 --> 00:36:58,600 I love it. Such good insights. 736 00:36:58,600 --> 00:37:00,600 Okay, final question for you. 737 00:37:00,600 --> 00:37:06,100 How do you personally define thriving and life and leadership? 738 00:37:06,100 --> 00:37:09,900 You know, I think I would answer that question 739 00:37:09,900 --> 00:37:13,400 by having the liberty to do what I want to do 740 00:37:13,400 --> 00:37:15,700 when I want to do it and with whom I want to do it. 741 00:37:16,700 --> 00:37:19,200 I love it, autonomy. 742 00:37:19,200 --> 00:37:22,700 Thank you so much for being here. 743 00:37:22,700 --> 00:37:25,700 So incredibly insightful. 744 00:37:25,700 --> 00:37:30,200 For those who want to take a deeper dive and learn more about you 745 00:37:30,200 --> 00:37:33,700 and your company, what is the best way for them to connect with you? 746 00:37:33,700 --> 00:37:37,700 You know, first, you have to read the book. 747 00:37:37,700 --> 00:37:39,700 This tells the story of nitric oxide. 748 00:37:39,700 --> 00:37:41,700 So in 30 minutes, we can't tell the whole story. 749 00:37:41,700 --> 00:37:42,700 But this is my book. 750 00:37:42,700 --> 00:37:44,200 I just published in February, 751 00:37:44,200 --> 00:37:45,200 Secretive Nitric Oxide, 752 00:37:45,200 --> 00:37:46,200 bring the science to life. 753 00:37:46,200 --> 00:37:50,200 You can find it at nathensbook.com or anywhere books are sold. 754 00:37:50,200 --> 00:37:56,200 Brian Therapeutics.com is our, you know, company website. 755 00:37:56,200 --> 00:37:59,200 You can find our consumer products at n101.com. 756 00:37:59,200 --> 00:38:02,200 It's the letter n, number one, letter o, number one. 757 00:38:02,200 --> 00:38:06,200 And I encourage you to subscribe to my YouTube channel, 758 00:38:06,200 --> 00:38:08,200 Dr. Nathan S. Brian Nitric Oxide, 759 00:38:08,200 --> 00:38:10,200 where we educate and form, bring you the latest science, 760 00:38:10,200 --> 00:38:12,200 practical information on Nitric Oxide 761 00:38:12,200 --> 00:38:15,200 and really practical applications you can, 762 00:38:15,200 --> 00:38:20,200 you can really adopt immediately to improve your nitric oxide production. 763 00:38:20,200 --> 00:38:23,200 And then I'm on Instagram, Dr. Nathan S. Brian linked in, 764 00:38:23,200 --> 00:38:26,200 and I'm searchable and most searching. 765 00:38:26,200 --> 00:38:29,200 I love it. 766 00:38:29,200 --> 00:38:33,200 Thank you so much for being here and sharing your time and knowledge 767 00:38:33,200 --> 00:38:35,200 with our listeners. 768 00:38:35,200 --> 00:38:38,200 That's the Executive Connect podcast. 769 00:38:38,200 --> 00:38:39,200 Thank you. 770 00:38:39,200 --> 00:38:39,800 Thank you.